Research

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The Matty Fund® awards grants for research projects that are committed to the prevention and advancement of new epilepsy discovery. As of the end of 2013 over $130,000 has been awarded to research projects led by CURE (Citizens United for Research in Epilepsy), Brown University and The University of Rhode Island.  The Matty Fund® encourages research studies which are not currently funded by the National Institutes of Health or other agencies. The Matty Fund® is committed to funding young scientists at Brown University’s Institute for Brain Science embarking on epilepsy research by establishing The Matthew Siravo Undergraduate Awards in Epilepsy Research.   This annual summer research award provides qualified Brown University undergraduate students with an opportunity to participate in a 10-week summer research program.  Recipients spend 35 hours a week for 10 weeks conducting research related to epilepsy or other seizure disorders in the laboratory of a faculty member of the Warren Alpert School of Medicine at Brown University.  An important part of the program is the education recipients receive related to the clinical realities of how patients live with epilepsy and how doctors treat this disease.  This award encourages work toward improving the diagnosis, treatment and prevention of epilepsy.

The Matty Fund’s® Medical Advisory Board reviews all epilepsy research applications.

The Matty Fund’s ® Epilepsy Research Symposium encourages scientists and clinicians to collaborate on epilepsy research initiatives. There is an essential need for greater funding and the Matty Fund® seeks the support of donors committed to the advancement of epilepsy research.

Medical Advisory Board

John Gaitanis, M.D., Chairman
R. John Davenport, Ph.D.
Roger Fazio, M.D.
David Mandelbaum, M.D.
Mrs. Jessica Mulligan, MS, RD, LDN
Mrs. Maura Taylor
Mrs. Karen Zelano, RN, CPN

Matty Fund® Research Award Recipients

Nicholas Poolos, M.D., Ph.D. – Kinase Mediation of Antiepileptic Drug Action

W. Curt La France, Jr. M.D., Ph.D. – A Lab Test for Differentiating between Epilepsy and Non-Epileptic Seizures

John Gaitanis, M.D. – Applying Information Theory Analysis to the Diagnosis of Epilepsy

Walter G. Besio, M.D. – Transcutaneous Electrical Stimulation via Concentric Ring Electrodes for Epilepsy

James Belarde & Carlos Aizenman, Ph.D. – Analyzing the Seizure Behavior of Xenopus Laevis Tadpole Animal Model

Susie Lee & Barry Connors, Ph.D. – Understanding the Basic Mechanisms of Febrile Seizures –the Most Prevalent Type of Seizure in Infancy and Early Childhood

Hannah Johnson & Carlos Aizenman, Ph.D. – The Study of Polymines and their Ant-Seizure Role in the Brain.*  Click here to read an update…

Nicholas Donias & Barry Connors, Ph.D. –Understanding how the Neural Circuits of the Prefrontal Cortex are Modified by a Type of Brain Oscillation.

Maria DeLuca & W. Curt La France Jr., M.D., Ph.D. – Neuroimaging analysis of the epilepsy-depression phenotype

Subhandra Sundaram & Eric Morrow, M.D., Ph.D. – Clinical and statistical genetic studies in autism with epilepsy

Rohan Ramesh & Rebecca Burwell, Ph.D. - Understanding entorhinal-hippocampal interactions in epilepsy

Jenny Gu & Carlos Aizenman, Ph.D. – Epilepsy in a tadpol model of neural development

Sudhandra Sundaram & Curt LaFrance, M.D., Ph.D. – Cognition and Psychogenic Nonepileptic (PNES) in Children

David Stein & Eric Morrow, M.D., Ph.D. – Investigating the Effects of Human NHE6 Mutations in Neurodevelopment, Neurodegeneration and Epilepsy

 

A thank you from one of our recipients:

“To the founders and organizers of The Matty Fund,
I am writing to thank you for the funding I received this past summer to conduct research on epilepsy and depression. I’m a senior undergraduate at Brown University and have been working on a neuroimaging study on the structural differences between epilepsy with and without comorbid depression. The project began this past summer and, with the help of the Matthew Siravo Undergraduate Award in Epilepsy, I was able to work as a research assistant collecting and analyzing data and shadowing Dr. Andrew Blum and Dr. David Mandelbaum at Rhode Island Hospital. I am still involved with the project, which is actively recruiting subjects, and I am also working on a senior thesis analyzing the data we have collected so far.
Next semester I begin medical school at Warren Alpert and after shadowing Dr. Mandelbaum, I have began considering pediatrics as a possible field to pursue. Thank you so much for this opportunity, I really appreciate having been able to participate in this research and learn more about diagnoses and treatment in epilepsy.
Sincerely,
Marie DeLuca
Brown 2012/PLME 2016 ”

 

*Matthew Siravo Research Awards in the News:
Matthew Siravo Research Awards to Hannah Johnson & James Belarde of Brown University being recognized. PROVIDENCE, R.I. [Brown University] — For years brain scientists have puzzled over the shadowy role played by the molecule putrescine, which always seems to be present in the brain following an epileptic seizure, but without a clear indication whether it was click link below to read more:
New role for an old molecule: protecting the brain from epileptic seizures | Brown University News anews.brown.edu